Document Details

Document Type : Article In Journal 
Document Title :
Possible impact of mutations against antimalarials on phenotypic expression of Plasmodium falciparum and Plasmodium vivax
التأثير المحتمل لتحول الطفرات بسبب الادوية المضادة للملاريا على اشكال الملاريا المنجلية والملاريا الفايفكسية
 
Subject : malaria 
Document Language : English 
Abstract : Polymorphism is observed in the signet ring stage of plasmodium falciparum and P.vivax. In 5-10% of patients of Sudan, Yemen, Ethiopia and Jezan of Saudi Arabia, rings were of very small size ranging from 0.7-2 um both round and oblong with cytoplasm of non-uniform thickness, while in 30% patients, rings were slightly oblong and bigger (i.e. 2-3 um) with non-uniform thickness. Alteration in size of P.vivax ring was also observed in about 10% patients in whom rings were slightly smaller (2-3um) than that of its usual size showing resemblance with P.falciparum ring. Variations in ring shape were also observed in 10% P.falciparum cases in the patients of Bangladesh, Pakistan and India. This polymorphism in Plasmodium with different phenotypic expressions seems to be due to the mutations against anti-malarial, frequently used to treat resistant cases of malaria. 
ISSN : 0972-6683 
Journal Name : Proceedings of Zoology Sociaty India 
Volume : 1 
Issue Number : 1 
Publishing Year : 1432 AH
2011 AD 
Article Type : Article 
Added Date : Monday, December 17, 2012 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
هيثم أحمد زكائيZakai, Haytham AhmedResearcherDoctoratehzakai@kau.edu.sa
وجيه الله خانKhan, Wajihullah InvestigatorDoctoratewajihullahkhan@yahoo.co.in

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