Document Details Document Type : Article In Journal  Document Title : Peptides from human placenta: methionine enkephalin and substance P Peptides from human placenta: methionine enkephalin and substance P   Document Language : English  Abstract : Placenta Suppl. 1981;3:327-37. Peptides from human placenta: methionine enkephalin and substance P. Sastry BV, Tayeb OS, Barnwell SL, Janson VE, Owens LK. Abstract The occurrence of methionine enkephalin (379 pg/g tissue), beta-endorphin (448 pg/g tissue) and Substance P (2.4 pg/g tissue) in human placental villus were demonstrated by sensitive and specific radioimmunoassays. Conditions for the bioassay of placental extracts for enkephalin-like activities using the rat vas deferens were described. Substance P did not interfere in this bioassay. Comparison of the enkephalin-like activities determined by bioassay and the content of beta-endorphin and methionine enkephalin determined by radioimmunoassays indicated that placental villus extracts contain other unidentified potent opioid-like peptides or substances. It is suggested that methionine enkephalin and/or beta-endorphin and Substance P regulate release of acetylcholine or hormones from placental villus. Alternatively, these peptides may regulate sensory transmission (pain impulses) locally from the distended uterus during pregnancy or from the vaginal tract during childbirth  ISSN : 0143-4004  Journal Name : Placenta  Volume : 3  Issue Number : 1  Publishing Year : 1401 AH 1981 AD  Article Type : Article  Added Date : Thursday, March 31, 2011  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email أسامة طيب Tayeb, Osama Researcher Doctorate   Files File Name Type Description  29433.pdf pdf   Back To Researches Page