Document Details
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Document Type |
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Project |
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Document Title |
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Study the chemical constituents and the biological activity of citrullus colocynthus and cucumic perphetarum from cucurbitaceae دراسة التركيب الكيميائي والتأثير البيولوجي لعينات الحنظل والحيدوق من الفصيلة القرعية. |
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Subject |
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Study the chemical constituents and the biological activity of citrullus colocynthus and cucumic perphetarum from cucurbitaceae |
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Document Language |
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Arabic |
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Abstract |
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The growing interest in cucurbitacins as cucumic perphetarum is the result of the wide range of activities they exhibit toward plants, insects, and animals. They are known for their extreme bitterness, mammalian toxicity, their purgative, emetic, and cytotoxic effects, and as a source of insect antifeedants [1-3]. Recently, they were exploited for their antitumor properties, differential cytotoxicity toward renal, brain tumor, and melanoma cell lines [4], inhibition of cell adhesion [5], and kpossible antifungal effects [6] The fruits of citrullus colocynthis (Cuctirbitaceae), a plant indigenous to India, Pakistan and Sri Lanka have a variety of ethnomedical claims and finds uses as a purgative [7], powerful cathartic, abortifacient [8] and for amenorrhea [9]. Extracts derived from fruits of C. colocynthis have been shown to possess cardiac depressant, smooth muscle relaxant, cytotoxic, and antitumour activities [10]. Chemical investigations of the fruits of C. colocynthis by paper chromatography have revealed the presence of cucurbitacins and the glucosides of cucurbitacins [11]. So we are interest to study the chemical constituents and the biological activity of citrullus colocynthus, cucumic perphetarum which collected from the Kingdom of Saudi Arabia and optimize the utilization of such products and encourage some of the pharmaceutical companies to produce this product in the suitable form. |
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Publishing Year |
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1428 AH
2007 AD |
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Added Date |
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Monday, June 28, 2010 |
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Researchers
| سالم أحمد باسيف | Ba-Saif, Salem Ahmad | Investigator | Doctorate | |
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