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Document Type |
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Article In Journal |
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Document Title |
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Morphological profile of testicular biopsies associated with infertility at University Hospital. Morphological profile of testicular biopsies associated with infertility at University Hospital. |
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Document Language |
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English |
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Abstract |
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Based on testicular biopsies examined at King
Abdulaziz University Hospital, Jeddah, Kingdom of Saudi
Arabia, the goal of this retrospective study is identification
and systemization of the histopathological patterns of
testicular biopsies received especially for investigating
male infertility and further more to compare the findings
of our study with similar studies in the literature.
Methods: Our study group consisted of 164 testicular
biopsies, which were examined in the Department of
Histopathology at King Abdulaziz University Hospital in
Jeddah, over a period of 10 years. The data was retrieved
and analyzed and the available histopathological results
were grouped into 8 different morphological categories.
Results: The findings of the biopsies associated with
infertility were complied as follows: 45 (27%) showed
normal spermatogenesis of which 15% showed active
From the Department of Histopathology, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia.
Received 28th February 2001. Accepted for publication in final form 30th April 2001.
Address correspondence and reprint request to: Dr. Awatif Jamal, Department of Histopathology, King Abdulaziz University, PO Box 6615, Jeddah
21452, Kingdom of Saudi Arabia. Fax. +966 (2) 6403975. E-mail: imb979@hotmail.com
spermatogenesis associated with duct obstruction, 41
(25%) with hypospermatogenesis, 39 (24%) showed end
stage tubular sclerosis with interstitial fibrosis, 27 (16.5%)
with germ cell aplasia (with or without focal
spermatogenesis), 11 (7%) biopsies showed maturation
arrest and only on biopsy were associated with karyotpic
abnormalities.
Conclusion: A higher percentage of hypospermatogenesis
and end stage tubular sclerosis with interstitial fibrosis
was noticed in this study when compared with the other
studies reported from Saudi Arabia. A high percentage
(27%) of the biopsies show normal spermatogenesis with
or without duct obstruction.
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ISSN |
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1658-3175 |
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Journal Name |
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Saudi Medical Journal |
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Volume |
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22 |
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Issue Number |
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11 |
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Publishing Year |
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1421 AH
2001 AD |
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Article Type |
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Article |
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Added Date |
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Monday, May 17, 2010 |
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Researchers
| عواطف جمال | Jamal, Awatif | Researcher | Doctorate | Awatjamal@yahoo.com |
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